The only betting I've ever done in a game was on Super Smash Bros., and even then I grew tired of it. I prefer playing.
In general, though, I hate gambling, even moreso when real money is involved. It's a terrible habit to get into and it can degenerate faster than you can realize it, it takes nothing to start rolling down. Plus, every time betting is involved you'll be guaranteed to find a shady scheme behind it, which should further discourage the thought (it ever crossed your mind in the first place).