New game? As in a game that came out in the past 2 years?
If that's the case, it has to be Fallout 4. While some may find the game lacking, I found its new features to be quite enjoyable, specifically the new Power Armor. The story had a huge plot twist and doesn't seem too cliché. While not living up to the expectations set by its predecessors Fallout 3 and New Vegas, it was still a decent and enjoyable experience for me. And of course, the classic Fallout-style dialogues lead to endless possibilities for different characters, requiring hundreds of hours to fully explore all options.
And all that doesn't include DLC.